"Can't Deny My Love" was met with positive reception upon its release. PopJustice gave the song a positive review describing it as "Haim meets Pet Shop Boys meets The Killers" and added "it's really amazing so tune in".
Digital Spy gave it five stars out of five calling it, "big, bold, and quite possibly one of the best songs Flowers has sung on this decade." Music Times also gave the song a positive review calling it "a glowing effort of what a new solo single could be - it's fitting in the 2015 pop landscape all while maintaining the very thing that makes Flowers a unique presence in music over a decade into his career." Gigwise reported that "it confirms why The Desired Effect is one of our most anticipated records of the year.”